Diabetes Care ( IF 16.2 ) Pub Date : 2021-12-01 , DOI: 10.2337/dc21-1373 Elena Toschi 1, 2, 3 , Amy Michals 4 , Atif Adam 4 , Dai'Quann Davis 4 , Astrid Atakov-Castillo 4 , Christine Slyne 4 , Medha Munshi 2, 3, 4
To assess the relationship between the glucose management indicator (GMI) and HbA1c in non-White individuals with diabetes.
We performed a retrospective analysis of continuous glucose monitoring metrics in individuals with diabetes divided by race into non-White and White cohorts.
We evaluated 316 individuals (non-White n = 68; White n = 248). Although GMI was not different (7.6 vs. 7.7; P = not significant) between the cohorts, HbA1c was higher in the non-White cohort (8.7% vs. 8.1%; P = 0.004). HbA1c higher than GMI by ≥0.5% was more frequently observed in the non-White cohort (90% vs. 75%; P = 0.02). In the non-White cohort only, duration of hypoglycemia was longer among those with HbA1c higher than GMI by ≥0.5% compared with those with HbA1c and GMI within 0.5%.
A differential relationship between HbA1c and GMI in non-White versus White individuals with diabetes was observed. In non-White individuals, a greater difference between HbA1c and GMI was associated with higher risk of hypoglycemia.
中文翻译:
CGM 衍生指标(葡萄糖管理指标)对评估非白人糖尿病患者血糖控制的有用性
评估非白人糖尿病患者的葡萄糖管理指标 (GMI) 和 HbA 1c之间的关系。
我们对按种族分为非白人和白人队列的糖尿病患者的连续血糖监测指标进行了回顾性分析。
我们评估了 316 个人(非白人n = 68;白人n = 248)。尽管队列之间的 GMI 没有差异(7.6 对 7.7;P = 不显着),但非白人队列中的HbA 1c更高(8.7% 对 8.1%; P = 0.004)。在非白人队列中更常观察到HbA 1c比 GMI 高 ≥ 0.5%(90% 对 75%;P = 0.02)。仅在非白人队列中,与 HbA 1c和 GMI 在 0.5% 以内的患者相比,HbA 1c高于 GMI ≥ 0.5% 的患者低血糖持续时间更长。
观察到非白人与白人糖尿病患者的HbA 1c和 GMI之间存在差异关系。在非白人个体中,HbA 1c和 GMI 之间的较大差异与较高的低血糖风险相关。