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rECHOmmend: an ECG-based machine-learning approach for identifying patients at high-risk of undiagnosed structural heart disease detectable by echocardiography
medRxiv - Cardiovascular Medicine Pub Date : 2021-10-07 , DOI: 10.1101/2021.10.06.21264669
Alvaro E Ulloa-Cerna , Linyuan Jing , John M Pfeifer , Sushravya Raghunath , Jeffrey A Ruhl , Daniel B Rocha , Joseph B Leader , Noah Zimmerman , Greg Lee , Steven R Steinhubl , Christopher W Good , Christopher M Haggerty , Brandon K Fornwalt , RuiJun Chen

Background Early diagnosis of structural heart disease improves patient outcomes, yet many remain underdiagnosed. While population screening with echocardiography is impractical, electrocardiogram (ECG)-based prediction models can help target high-risk patients. We developed a novel ECG-based machine learning approach to predict multiple structural heart conditions, hypothesizing that a composite model would yield higher prevalence and positive predictive values (PPVs) to facilitate meaningful recommendations for echocardiography.

中文翻译:

rECHOmmend:一种基于心电图的机器学习方法,用于识别超声心动图可检测到的未确诊结构性心脏病的高风险患者

背景结构性心脏病的早期诊断可改善患者的预后,但仍有许多未被确诊。虽然使用超声心动图进行人群筛查不切实际,但基于心电图 (ECG) 的预测模型可以帮助定位高危患者。我们开发了一种新的基于 ECG 的机器学习方法来预测多种结构性心脏病,假设复合模型会产生更高的患病率和阳性预测值 (PPV),以促进对超声心动图的有意义的建议。
更新日期:2021-10-10
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