PURPOSE/OBJECTIVE To examine the association between physical and mental symptoms and cognition in people with spinal cord injury. Research Method/Design: One hundred seventy-four community-dwelling adults with spinal cord injury completed several self-reported measures of health-related quality of life (Patient-Reported Outcomes Measurement Information System [PROMIS] Cognitive Abilities, Anxiety, Depression, Fatigue, and Pain Intensity) as well as a traditional neuropsychological assessment (six tests that included assessments of processing speed, working memory, memory, executive function, and attention). A series of multivariable linear regressions were used to test for associations between physical and mental symptoms and the seven ratings of cognition (i.e., scores on PROMIS Cognitive Abilities, as well as the six scores from the neuropsychological tests) after controlling for age, gender, education, and injury classification. RESULTS There was generally no association between symptom measures and neuropsychological test performance with one exception: Greater pain was associated with poorer performance on attention. However, anxiety and fatigue were associated with lower self-perceived cognitive function. Among those individuals with evidence of cognitive impairment in at least one cognitive domain, anxiety was also associated with lower working memory score, and fatigue was associated with lower delayed memory performance. CONCLUSIONS/IMPLICATIONS While the associations between pain and cognitive performance are consistent with general literature, the absence of a relationship between other symptoms (i.e., depression and fatigue) and cognitive performance was somewhat more surprising. Similarly, the associations between anxiety and fatigue with perceived cognitive function are consistent with the general literature, yet the absence of a relationship with depression was somewhat more surprising. Future work is needed to replicate these findings. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

中文翻译：

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脊髓损伤患者的身体和精神症状与认知的关联。

目的/目的 研究脊髓损伤患者的身体和精神症状与认知之间的关系。研究方法/设计：174 名患有脊髓损伤的社区居民完成了多项自我报告的健康相关生活质量测量（患者报告的结果测量信息系统 [PROMIS] 认知能力、焦虑、抑郁、疲劳）和疼痛强度）以及传统的神经心理学评估（六项测试，包括评估处理速度、工作记忆、记忆、执行功能和注意力）。一系列多变量线性回归用于测试身体和精神症状与认知的七个等级之间的关联（即 PROMIS 认知能力得分，以及来自神经心理学测试的六个分数）在控制了年龄、性别、教育和伤害分类后。结果 症状测量与神经心理学测试表现之间通常没有关联，但有一个例外：更大的疼痛与较差的注意力表现相关。然而，焦虑和疲劳与较低的自我认知认知功能有关。在至少一个认知领域有认知障碍证据的个体中，焦虑也与较低的工作记忆评分相关，而疲劳与较低的延迟记忆表现相关。结论/意义 虽然疼痛和认知能力之间的关联与一般文献一致，但其他症状之间没有相关性（即，抑郁和疲劳）和认知表现更令人惊讶。同样，焦虑和疲劳与感知认知功能之间的关联与一般文献一致，但与抑郁症没有关系则更令人惊讶。未来的工作需要复制这些发现。（PsycInfo 数据库记录 (c) 2021 APA，保留所有权利）。