Referrals of transgender and gender-diverse (trans) youth to medical clinics for gender-affirming care have increased. We described characteristics of trans youth in Canada at first referral visit.

Baseline clinical and survey data (2017–2019) were collected for Trans Youth CAN!, a 10-clinic prospective cohort of n = 174 pubertal and postpubertal youth <16 years with gender dysphoria, referred for hormonal suppression or hormone therapy, and 160 linked parent-participants. Measures assessed health, demographics, and visit outcome.

Of youth, 137 were transmasculine (assigned female) and 37 transfeminine (assigned male); 69.0% were aged 14 to 15, 18.8% Indigenous, 6.6% visible minorities, 25.7% from immigrant families, and 27.1% low income. Most (66.0%) were gender-aware before age 12. Only 58.1% of transfeminine youth lived in their gender full-time versus 90.1% of transmasculine (P < .001). Although transmasculine youth were more likely than transfeminine youth to report depressive symptoms (21.2% vs 10.8%; P = .03) and anxiety (66.1% vs 33.3%; P < .001), suicidality was similarly high overall (past-year ideation: 34.5%, attempts: 16.8%). All were in school; 62.0% reported strong parental gender support, with parents the most common support persons (91.9%). Two-thirds of families reported external gender-related stressors. Youth had met with a range of providers (68.5% with a family physician). At clinic visit, 62.4% were prescribed hormonal suppression or hormone therapy, most commonly depot leuprolide acetate.

Trans youth in Canada attending clinics for hormonal suppression or gender-affirming hormones were generally healthy but with depression, anxiety, and support needs.

将跨性别和性别多样化（跨性别）青年转介到医疗诊所接受性别肯定护理的情况有所增加。我们在第一次转诊时描述了加拿大跨性别青年的特征。

为 Trans Youth CAN! 收集了基线临床和调查数据（2017-2019 年），这是一个 10 个诊所的前瞻性队列，其中n = 174 名青春期和青春期后的青春期和青春期后的青少年<16 岁，患有性别焦虑症，转介进行激素抑制或激素治疗，以及 160 名相关的家长参与者。措施评估健康、人口统计和访问结果。

在青年中，137 名跨男性化（指定为女性）和 37 位跨女性化（指定为男性）；69.0% 为 14 至 15 岁，18.8% 原住民，6.6% 有色人种，25.7% 来自移民家庭，27.1% 低收入。大多数 (66.0%) 在 12 岁之前就具有性别意识。只有 58.1% 的跨性别青年与 90.1% 的跨男性青年 ( P < .001)保持同性别的全职生活。尽管跨男性青年比跨女性青年更有可能报告抑郁症状（21.2% 对 10.8%；P = .03）和焦虑（66.1% 对 33.3%；P< .001)，总体上自杀倾向同样高（过去一年的想法：34.5%，尝试：16.8%）。所有人都在学校；62.0% 的人报告了强烈的父母性别支持，其中父母是最常见的支持者 (91.9%)。三分之二的家庭报告了与性别相关的外部压力。青年会见了一系列提供者（68.5% 的人有家庭医生）。就诊时，62.4% 的患者接受了激素抑制或激素治疗，最常见的是长效醋酸亮丙瑞林。

加拿大的跨性别青年到诊所接受激素抑制或性别肯定激素治疗，他们总体上是健康的，但有抑郁、焦虑和支持需求。