Although growth differentiation factor 15 (GDF15) is known to increase with disease and is associated with low physical performance, the role of GDF15 in normal ageing is still not fully understood. Specifically, the influence of circulating GDF15 on impairments in maximal muscle power (a major contributor to functional limitations) and the underlying components has not been investigated.

中文翻译：

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整个成年期系统性 GDF15 的变化及其对最大肌肉力量的影响：哥本哈根肌肉减少症研究

尽管已知生长分化因子 15 (GDF15) 会随着疾病增加并与身体机能低下有关，但 GDF15 在正常衰老中的作用仍不完全清楚。具体而言，尚未研究循环 GDF15 对最大肌肉力量损伤（功能限制的主要因素）和潜在成分的影响。