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Cone beam computed tomography and image registration based on target area for stereotactic body radiation therapy of lung cancer
Journal of Radiation Research and Applied Sciences ( IF 1.7 ) Pub Date : 2021-10-04 , DOI: 10.1080/16878507.2021.1981754
Long-Gang Gui 1 , Miao Shi 1 , Jun Li 1
Affiliation  

ABSTRACT

This paper aims to compare the dosimetric parameters of the original plan and the simulated plan to explore the clinical value of cone beam CT and planned CT image registration based on the target area. The results showed that Dmax, Dmin, dmean and V60 of PTV in the original plan were (108.3 ± 1.1)%, (97.2 ± 0.3)%, (102.6 ± 0.6)% and (95.2 ± 0.6)% respectively. The Dmax of spinal cord was (9.6 ± 1.8) gy, the V20 of lung was (5.2 ± 1.9)%, and the dmean of lung was (− 3.7 ± 1.5) gy; however, when the target area was translated in the three directions of the patient's back, right side and foot, the dosimetric parameters of the target area (Dmax, Dmin and V60), dmean and V20 of lung and Dmax of spinal cord showed slight differences, which all met the limit requirements of target area and dangerous organs (OARs) (RTOG) 0915 report. Therefore, target based image registration is feasible. If the registration translation error is less than or equal to 1 cm, there is no need to re move the treatment bed according to the registration error.



中文翻译:

基于目标区域的锥形束计算机断层扫描和图像配准用于肺癌立体定向放射治疗

摘要

本文旨在通过比较原始计划和模拟计划的剂量学参数,探讨锥束CT和基于目标区域的计划CT图像配准的临床价值。结果表明,原计划中PTV的Dmax、Dmin、dmean和V60分别为(108.3±1.1)%、(97.2±0.3)%、(102.6±0.6)%和(95.2±0.6)%。脊髓Dmax为(9.6±1.8)gy,肺V20为(5.2±1.9)%,肺dmean为(-3.7±1.5)gy;然而,当靶区向患者背部、右侧和足部三个方向平移时,靶区的剂量学参数(Dmax、Dmin 和 V60)、肺的 dmean 和 V20 以及脊髓的 Dmax 显示出轻微的差异。 , 均满足目标区域和危险器官 (OARs) (RTOG) 0915 报告的限制要求。所以,基于目标的图像配准是可行的。如果配准平移误差小于等于1 cm,则无需根据配准误差重新移动治疗床。

更新日期:2021-10-06
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