Rifamycins, such as rifampicin, are potent inhibitors of bacterial RNA polymerases and widely used antibiotics. Usually rifamycin-resistance is associated with mutations in RNAP that preclude rifamycins binding. However, some bacteria have ADP-ribosyl ...

中文翻译：

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康乐霉素 A 可克服 Arr 蛋白 ADP 核糖基化引起的利福霉素耐药性

利福霉素，如利福平，是细菌 RNA 聚合酶和广泛使用的抗生素的有效抑制剂。通常，利福霉素抗性与阻止利福霉素结合的 RNAP 突变有关。然而，一些细菌具有 ADP-核糖基...