Population pharmacokinetic-pharmacodynamic model of oxfendazole in healthy adults in a multiple ascending dose and food effect study and target attainment analysis,Antimicrobial Agents and Chemotherapy

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Population pharmacokinetic-pharmacodynamic model of oxfendazole in healthy adults in a multiple ascending dose and food effect study and target attainment analysis
Antimicrobial Agents and Chemotherapy ( IF 4.9 ) Pub Date : 2021-10-04 , DOI: 10.1128/aac.01432-21
Thanh Bach ₁ , Gregory A Deye ₂ , Ellen E Codd _{3,

4} , John Horton _{4,

5} , Patricia Winokur ₆ , Guohua An ₁

Affiliation

Oxfendazole is a potent veterinary antiparasitic drug undergoing development for human use to treat multiple parasitic infections. Results from two recently completed Phase I clinical trials conducted in healthy adults showed that the pharmacokinetics of ...

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