Mitochondrial dysfunction in skeletal muscle contributes to the development of acute insulin resistance in mice,Journal of Cachexia, Sarcopenia and Muscle

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Mitochondrial dysfunction in skeletal muscle contributes to the development of acute insulin resistance in mice
Journal of Cachexia, Sarcopenia and Muscle ( IF 8.9 ) Pub Date : 2021-10-03 , DOI: 10.1002/jcsm.12794
Hyunjung Lee ₁ , Tae Youl Ha _{1,

2} , Chang Hwa Jung _{1,

2} , Farida Sukma Nirmala _{1,

2} , So-Young Park ₃ , Yang Hoon Huh ₄ , Jiyun Ahn _{1,

2}

Affiliation

Although mounting evidence indicates that insulin resistance (IR) co-occurs with mitochondrial dysfunction in skeletal muscle, there is no clear causal link between mitochondrial dysfunction and IR pathogenesis. In this study, the exact role of mitochondria in IR development was determined.

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