Vernal keratoconjunctivitis is a chronic allergic conjunctivitis with corneal involvement that affects children and adolescents. Its pathogenic mechanisms are not entirely clear, but IgE and other inflammatory mediators are involved. An 8-year-old boy with vernal keratoconjunctivitis not responding to conventional treatment started immunotherapy with good results, decreasing the topical steroid dependence. Conventional vernal keratoconjunctivitis treatment involves topical antihistamines and steroids. These are not always effective and steroids can be associated with severe ocular complications in the long term. The authors suggest searching for possible allergens and starting immunotherapy associated with conventional topical treatment earlier, in addition to measuring the health-related quality of life by applying the Quality of Life in Children with Vernal Keratoconjunctivitis questionnaire and adjusting the treatment according to the impact on patients' quality of life. [J Pediatr Ophthalmol Strabismus. 2021;58(5):e36-e39.].

中文翻译：

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春季角结膜炎：超越经典治疗。

春季角结膜炎是一种慢性过敏性结膜炎，角膜受累影响儿童和青少年。其致病机制尚不完全清楚，但与IgE等炎症介质有关。一名患有春季角结膜炎的 8 岁男孩对常规治疗无反应，开始免疫治疗并取得良好效果，减少了局部类固醇依赖。传统的春季角结膜炎治疗包括局部使用抗组胺药和类固醇。这些并不总是有效，从长远来看，类固醇可能与严重的眼部并发症有关。作者建议寻找可能的过敏原并尽早开始与常规局部治疗相关的免疫治疗，此外，还通过应用春季角结膜炎儿童生活质量问卷来衡量与健康相关的生活质量，并根据对患者生活质量的影响调整治疗方案。[J Pediatr Ophthalmol 斜视。2021;58(5):e36-e39.]。