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Occult Colon Adenocarcinoma and Multiple Myeloma Associated With Clostridium septicum Panophthalmitis With Orbital and Chiasmal Extension: A Case Report.
Ophthalmic Plastic and Reconstructive Surgery ( IF 2 ) Pub Date : 2021-09-28 , DOI: 10.1097/iop.0000000000002056
Arian Ghanouni 1 , Sarah A Avila 2 , H Joon Kim 2
Affiliation  

A previously healthy 62-year-old African American female presented with a fulminant orbital cellulitis of the right eye with diffuse scleritis and orbital inflammation extending to the optic chiasm on neuroimaging. She was taken for an emergent orbitotomy with an orbital fat biopsy and started on broad-spectrum intravenous (IV) and topical antibiotics. Within 36 hours of presentation, scleral thinning and a corneal melt ensued, ending in enucleation. Intraoperative cultures were positive for Clostridium septicum, leading to a systemic work-up exposing a previously undiagnosed colon adenocarcinoma and metastatic multiple myeloma.

中文翻译:

隐匿性结肠腺癌和多发性骨髓瘤与败血梭状芽胞杆菌全眼炎伴眼眶和交叉延伸:病例报告。

一名先前健康的 62 岁非洲裔美国女性因右眼暴发性眼眶蜂窝织炎而就诊,神经影像学显示伴有弥漫性巩膜炎和眼眶炎症延伸至视交叉。她接受了紧急眼眶切开术和眼眶脂肪活检,并开始接受广谱静脉注射 (IV) 和局部抗生素治疗。就诊后 36 小时内,巩膜变薄,角膜融化,最终摘除角膜。术中培养对败血梭状芽胞杆菌呈阳性,导致系统检查暴露出先前未诊断的结肠腺癌和转移性多发性骨髓瘤。
更新日期:2021-09-28
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