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Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination
Emerging Infectious Diseases ( IF 11.8 ) Pub Date : 2021-09-24 , DOI: 10.3201/eid2711.211612 Heather N Grome , Michael Threlkeld , Steve Threlkeld , Charles Newman , Roosecelis Brasil Martines , Sarah Reagan-Steiner , Michael A Whitt , Maria Gomes-Solecki , Nisha Nair , Mary-Margaret Fill , Timothy F Jones , William Schaffner , John Dunn
中文翻译:
SARS-CoV-2 自然感染和 COVID-19 疫苗接种后成人致命性多系统炎症综合征
更新日期:2021-10-09
Emerging Infectious Diseases ( IF 11.8 ) Pub Date : 2021-09-24 , DOI: 10.3201/eid2711.211612 Heather N Grome , Michael Threlkeld , Steve Threlkeld , Charles Newman , Roosecelis Brasil Martines , Sarah Reagan-Steiner , Michael A Whitt , Maria Gomes-Solecki , Nisha Nair , Mary-Margaret Fill , Timothy F Jones , William Schaffner , John Dunn
We describe a fatal case of multisystem inflammatory syndrome in an adult with onset 22 days after a second dose of mRNA coronavirus disease vaccine. Serologic and clinical findings indicated severe acute respiratory syndrome coronavirus 2 infection occurred before vaccination. The immunopathology of this syndrome, regardless of vaccination status, remains poorly understood.
中文翻译:
SARS-CoV-2 自然感染和 COVID-19 疫苗接种后成人致命性多系统炎症综合征
我们描述了一例成人多系统炎症综合征的致命病例,该病例在第二剂 mRNA 冠状病毒病疫苗接种后 22 天发作。血清学和临床发现表明严重急性呼吸系统综合症冠状病毒 2 感染发生在接种疫苗之前。无论疫苗接种情况如何,这种综合征的免疫病理学仍然知之甚少。