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Nanocellulose-based Delivery Systems and Cervical Cancer: Review of the Literature
Current Pharmaceutical Design ( IF 3.1 ) Pub Date : 2021-11-30 , DOI: 10.2174/1381612827666210927110937
Fatemeh Sadoughi 1 , Jamal Hallajzadeh 2 , Zatollah Asemi 1 , Mohammad A Mansournia 3 , Bahman Yousefi 4
Affiliation  

It has become clear that targeted therapy is one of the best options for decreasing the unpleasant side effects of existing common methods and reducing the number of deaths occurred due to many types of cancer. Biocompatible and non-toxic delivery systems are provided by nanomedicine for aiding targeted therapy in many diseases containing cancer. Cervical cancer (CC) is not only the most common gynecological cancer but also is ranked as the fourth common cancer between both men and women. Chemotherapy, radiotherapy, surgery, and immunotherapy are the approaches, which are being used for treating CC patients. However, more efficacy of these methods can be achieved with the help of nanomedicine and novel delivery systems. Nanocellulose is one of the agents used for designing these systems in order to deliver different drugs to a diversity of cancerous cells. In this review, we aim to investigate the competency of nanocellulose for establishing novel therapeutic methods for cervical cancer. We hope that our results help develop more drug delivery systems for targeted therapy to reduce the side effects and induce the efficacy of anti-cancer drugs.



中文翻译:

基于纳米纤维素的递送系统和宫颈癌:文献回顾

很明显,靶向治疗是减少现有常用方法的不良副作用和减少因多种癌症导致的死亡人数的最佳选择之一。纳米医学提供了生物相容和无毒的递送系统,用于帮助对许多含有癌症的疾病进行靶向治疗。宫颈癌(CC)不仅是最常见的妇科癌症,而且在男性和女性中排名第四。化学疗法、放射疗法、手术和免疫疗法是用于治疗CC患者的方法。然而,在纳米药物和新型递送系统的帮助下,可以实现这些方法的更多功效。纳米纤维素是用于设计这些系统的试剂之一,以便将不同的药物输送到多种癌细胞。在这篇综述中,我们旨在研究纳米纤维素在建立新的宫颈癌治疗方法方面的能力。我们希望我们的结果有助于开发更多用于靶向治疗的药物递送系统,以减少副作用并诱导抗癌药物的疗效。

更新日期:2021-11-24
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