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Impact of HIV-1 Resistance-associated Mutations on Susceptibility to Doravirine: Analysis of Real-world Clinical Isolates
Antimicrobial Agents and Chemotherapy ( IF 4.9 ) Pub Date : 2021-09-27 , DOI: 10.1128/aac.01216-21
Ernest Asante-Appiah 1 , Johnny Lai 2 , Hong Wan 1 , Dongmei Yang 2 , Elizabeth Anne Martin 1 , Peter Sklar 1 , Daria Hazuda 1 , Christos J Petropoulos 2 , Charles Walworth 2 , Jay A Grobler 1
Affiliation  

Background: Clinical management of human immunodeficiency virus type-1 (HIV-1) infection may be negatively impacted by either acquired or transmitted drug resistance. Here, we aim to extend our understanding of the impact of resistance-associated ...

中文翻译:

HIV-1 耐药相关突变对多拉韦林易感性的影响:真实世界临床分离株的分析

背景:人类免疫缺陷病毒 1 型 (HIV-1) 感染的临床管理可能受到获得性或传播性耐药性的负面影响。在这里,我们的目标是扩展我们对耐药性相关影响的理解……
更新日期:2021-09-29
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