Due to the highly growing number of available genomic information, the need for accessible and easy-to-use analysis tools is increasing. To facilitate eukaryotic genome annotations, we created MOSGA. In this work, we show how MOSGA 2 is developed by including several advanced analyses for genomic data. Since the genomic data quality greatly impacts the annotation quality, we included multiple tools to validate and ensure high-quality user-submitted genome assemblies. Moreover, thanks to the integration of comparative genomics methods, users can benefit from a broader genomic view by analyzing multiple genomic data sets simultaneously. Further, we demonstrate the new functionalities of MOSGA 2 by different use-cases and practical examples. MOSGA 2 extends the already established application to the quality control of the genomic data and integrates and analyzes multiple genomes in a larger context, e.g., by phylogenetics.

由于可用基因组信息的数量急剧增加，因此对可访问且易于使用的分析工具的需求正在增加。为了促进真核基因组注释，我们创建了 MOSGA。在这项工作中，我们展示了如何通过对基因组数据进行多项高级分析来开发 MOSGA 2。由于基因组数据质量极大地影响了注释质量，我们包含了多种工具来验证和确保用户提交的高质量基因组组装。此外，由于比较基因组学方法的整合，用户可以通过同时分析多个基因组数据集，从更广泛的基因组视图中受益。此外，我们通过不同的用例和实际示例展示了 MOSGA 2 的新功能。