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Parvimonas micra Necrotizing Panophthalmitis Involving the Sclera, Cornea, Uvea, Retina, and Orbit.
Ophthalmic Plastic and Reconstructive Surgery ( IF 2 ) Pub Date : 2021-09-24 , DOI: 10.1097/iop.0000000000002065
Jonathan A Barnett 1 , Katharine S Dempsey , Rachel K Sobel
Affiliation  

We present an unusual case of a patient who acquired a pansinusitis and orbital cellulitis with necrotizing features, subsequently developing scleritis, keratitis, and anterior uveitis. To date, there are no reported cases of the simultaneous involvement of these ocular structures from a pansinusitis. Our patient was urgently taken to the operating room for drainage of the abscesses within his sinuses and the orbit. Intraoperative cultures were positive for Parvimonas micra, an odontogenic anaerobic bacteria. He was additionally found to have a central retinal artery occlusion. He was treated with systemic and topical antibiotics as well as topical dilute hypochlorous acid. The mechanisms of virulence of P. micra, including its synergistic relationship with other bacteria, ability to bind plasminogen, and its expression of proteases, contributed to this diffuse infection.

中文翻译:

微单胞菌坏死性全眼炎,累及巩膜、角膜、葡萄膜、视网膜和眼眶。

我们介绍了一个不寻常的病例,患者患有全鼻窦炎和眼眶蜂窝织炎,并伴有坏死特征,随后出现巩膜炎、角膜炎和前葡萄膜炎。迄今为止,尚无全鼻窦炎同时累及这些眼部结构的病例报道。我们的患者被紧急送往手术室进行鼻窦和眼眶内脓肿的引流。术中培养结果显示,微小单胞菌(一种牙源性厌氧菌)呈阳性。他还被发现患有视网膜中央动脉闭塞。他接受了全身和局部抗生素以及局部稀次氯酸的治疗。P. micra 的毒力机制,包括其与其他细菌的协同关系、结合纤溶酶原的能力及其蛋白酶的表达,促成了这种弥漫性感染。
更新日期:2021-09-24
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