Gay, bisexual, and other men who have sex with men (GBMSM) in Nigeria bear a disproportionately higher burden of HIV. Meyer’s minority stress theory posits that social stress due to the discrimination, violence, and stigma experienced by lesbian, gay, and bisexual men and women (LGBs)—due to their sexual orientation—may contribute to psychological problems, including mental health problems, substance use, and HIV sexual risk-taking. Between March and June 2019, we recruited 406 GBMSM from four states in Nigeria (Abuja, Delta, Lagos, and Plateau) to complete a cross-sectional survey at local community-based organizations. We utilized structural equation modeling to test whether psychological problems and substance use mediated the relationship between minority stress and HIV sexual risk-taking (condomless anal sex and number of sexual partners) among GBMSM in Nigeria. Minority stress (β = 0.60, 95% CI: 0.44–0.72, p ≤ .001), substance use (β = 0.43, 95% CI: 0.27–0.59, p = .004), and psychological problems (β = 0.35, 95% CI: 0.28–0.45 p = .012) had moderate associations with HIV sexual risk-taking. We found that psychological problems mediated the relationship between minority stress and HIV sexual risk-taking. Interventions focused on addressing psychological problems may help mitigate the effects of minority stress on HIV sexual risk-taking among GBMSM in Nigeria.

在尼日利亚，同性恋、双性恋和其他男男性行为者 (GBMSM) 承受的艾滋病毒负担高得不成比例。迈耶的少数派压力理论认为，男女同性恋和双性恋男女 (LGB) 因其性取向而遭受的歧视、暴力和污名所导致的社会压力可能会导致心理问题，包括心理健康问题、物质使用和 HIV 性风险。2019 年 3 月至 6 月期间，我们从尼日利亚的四个州（阿布贾、三角洲、拉各斯和高原）招募了 406 名 GBMSM，以完成对当地社区组织的横断面调查。我们利用结构方程模型来测试心理问题和物质使用是否介导了尼日利亚 GBMSM 的少数族裔压力与 HIV 性风险（无安全套肛交和性伴侣数量）之间的关系。少数派压力（β  = 0.60, 95% CI: 0.44–0.72, p  ≤ .001), 物质使用 ( β  = 0.43, 95% CI: 0.27–0.59, p  = .004) 和心理问题 ( β  = 0.35, 95% CI) : 0.28–0.45 p  = .012) 与 HIV 性冒险有中度关联。我们发现心理问题介导了少数族裔压力与 HIV 性风险之间的关系。专注于解决心理问题的干预措施可能有助于减轻少数族裔压力对尼日利亚 GBMSM 中 HIV 性风险的影响。