Background: Adhatoda vasica (Nees.) of the family Acanthaceae has been used in the Southeast tropical zone as it is efficacious against headache, colds, cough, whooping cough, fever, asthma, dyspnea, phthisis, jaundice, chronic bronchitis, and diarrhea. It exhibits commendable pharmacological activities.

Objective: The aim of the review is to provide a systematic overview of pharmacological activities with toxicity and clinical assessment, phytochemistry of A. vasica along with its characterization, geographical observation, phenology, traditional uses, as well as an organized representation of the findings.

Method: The overall information of A. vasica was collected from various resources, including books, review papers, research papers, and reports which were obtained from an online search of globallyaccepted scientific databases. ChemDraw software was used to draw the compound’s structure.

Results: Phytochemical review on A. vasica has led to the collection of 233 compounds of different types such as alkaloids, flavonoids, essential oils, terpenoids, fatty acids, phenols, etc. It is a promising source of potential phytopharmaceutical agent that exhibits diverse pharmacological activities, including antibacterial, antifungal, hepatoprotective, anti-ulcer, abortifacient, antiviral, antiinflammatory, thrombolytic, hypoglycemic, anti-tubercular, antioxidant, and antitussive activities.

Conclusions: Sufficient number of studies on ethnopharmacology, traditional uses, and pharmacological activities of A. vasica are conducted. Furthermore, it is necessary to study the activity of chemical constituents for new drug design and discovery from natural products.

背景：棘皮科的刺槐 (Nees.) 已在东南热带地区使用，因为它可有效治疗头痛、感冒、咳嗽、百日咳、发烧、哮喘、呼吸困难、肺结核、黄疸、慢性支气管炎和腹泻。它表现出值得称道的药理活性。

目的：该评价的目的是系统概述药理活性、毒性和临床评估、A. vasica 的植物化学及其表征、地理观察、物候学、传统用途，以及研究结果的有组织的表示。

方法：从各种资源中收集 A. vasica 的整体信息，包括书籍、评论论文、研究论文和通过在线搜索全球公认的科学数据库获得的报告。ChemDraw 软件用于绘制化合物的结构。

结果：A. vasica 的植物化学研究收集了 233 种不同类型的化合物，如生物碱、黄酮类化合物、精油、萜类化合物、脂肪酸、酚类等。活性，包括抗菌、抗真菌、保肝、抗溃疡、流产、抗病毒、抗炎、溶栓、降血糖、抗结核、抗氧化和镇咳活性。

结论：对 A. vasica 的民族药理学、传统用途和药理活性进行了足够数量的研究。此外，有必要研究化学成分的活性，以便从天然产物中设计和发现新药。