Calcium ion (Ca²⁺) signaling is one of the most frequently employed mechanisms of signal transduction by eukaryotic cells, and starts with either Ca²⁺ release from intracellular stores or Ca²⁺ entry through the plasma membrane. In intracellular protist parasites Ca²⁺ signaling initiates a sequence of events that may facilitate their invasion of host cells, respond to environmental changes within the host, or regulate the function of their intracellular organelles. In this review we examine recent findings in Ca²⁺ signaling in two groups of intracellular protist parasites that have been studied in more detail, the apicomplexan and the trypanosomatid parasites.

钙离子 (Ca ²⁺ ) 信号转导是真核细胞最常用的信号转导机制之一，从细胞内储存的 Ca ²⁺释放或 Ca ²⁺通过质膜进入开始。在细胞内原生生物寄生虫中，Ca ²⁺信号启动了一系列事件，这些事件可能有助于它们入侵宿主细胞、响应宿主内的环境变化或调节其细胞内细胞器的功能。在这篇综述中，我们检查了两组细胞内原生生物寄生虫（顶端复合体和锥虫寄生虫）中 Ca ^{2+信号传导的最新发现，这些寄生虫已被更详细地研究。}