To compare refractive outcomes after cataract surgery in pseudoexfoliation syndrome (PEX) and control eyes and to investigate the accuracy of 3 intraocular lens (IOL) calculation formulas in these eyes. In this prospective comparative study 42 eyes (PEX group) and 38 eyes (control group) of 80 patients were included. The follow-up was 3 months. The refractive prediction error (RPE), mean absolute error (MAE), median absolute error (MedAE) and the percentages of eyes within ± 0.25 D, ± 0.5 D, ± 1.0 D and ± 2.0 D of prediction error were calculated. Three IOL calculation formulas (SRK/T, Barrett Universal II and Hill-RBF) were evaluated. PEX produced statistically significantly higher mean absolute errors and lower percentages of eyes within ± 0.5 D than control eyes in all investigated IOL calculation formulas. There were no statistically significant differences in the median absolute errors between the 3 formulas in either PEX or control eyes. Refractive outcomes after cataract surgery are statistically significantly worse in PEX than in control eyes. All three IOL calculation formulas produced similar results in both PEX and control eyes.

Trial registration: ClinicalTrials.gov registration number NCT04783909.

比较假性剥脱综合征 (PEX) 和对照眼白内障手术后的屈光结果，并研究这些眼中 3 种人工晶状体 (IOL) 计算公式的准确性。在这项前瞻性比较研究中，包括 80 名患者的 42 只眼（PEX 组）和 38 只眼（对照组）。随访3个月。计算屈光预测误差 (RPE)、平均绝对误差 (MAE)、中值绝对误差 (MedAE) 和±0.25 D、± 0.5 D、± 1.0 D 和± 2.0 D 预测误差内的眼睛百分比。评估了三个 IOL 计算公式（SRK/T、Barrett Universal II 和 Hill-RBF）。在所有研究的人工晶状体计算公式中，PEX 产生的平均绝对误差在统计上显着更高，±0.5 D 内的眼睛百分比低于对照眼。在 PEX 或对照眼中，3 个公式之间的中值绝对误差没有统计学上的显着差异。白内障手术后的屈光结果在 PEX 中显着低于对照眼。所有三个 IOL 计算公式在 PEX 和对照眼中产生了相似的结果。

试验注册： ClinicalTrials.gov 注册号 NCT04783909。