Type 1 diabetes mellitus and polycystic ovary syndrome,Nature Reviews Endocrinology

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Type 1 diabetes mellitus and polycystic ovary syndrome
Nature Reviews Endocrinology ( IF 40.5 ) Pub Date : 2021-09-24 , DOI: 10.1038/s41574-021-00576-0
Héctor F Escobar-Morreale _{1,

2,

3,

4} , Ane Bayona _{1,

3,

4} , Lía Nattero-Chávez _{1,

3,

4} , Manuel Luque-Ramírez _{1,

2,

3,

4}

Affiliation

Up to one in four women with type 1 diabetes mellitus (T1DM) also have polycystic ovary syndrome (PCOS). Under subcutaneous insulin administration, systemic hyperinsulinism might trigger PCOS in women predisposed to the condition. However, very little is known about the long-term consequences of androgen excess in women with T1DM, and management guidelines are lacking.

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