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Deciphering mouse uterine receptivity for embryo implantation at single-cell resolution
Cell Proliferation ( IF 8.5 ) Pub Date : 2021-09-23 , DOI: 10.1111/cpr.13128
Yi Yang 1 , Qiu-Yang Zhu 2 , Ji-Long Liu 2
Affiliation  

Mice are widely used as an animal model for studying human uterine receptivity for embryo implantation. Although transcriptional changes related to mouse uterine receptivity have been determined by using bulk RNA-seq, the data are of limited value because the uterus is a complex organ consisting of many cell types. Here, we aimed to decipher mouse uterine receptivity for embryo implantation at single-cell resolution.

中文翻译:

以单细胞分辨率破译小鼠子宫对胚胎植入的接受性

小鼠被广泛用作研究人类子宫接受胚胎植入的动物模型。尽管已经通过使用大量 RNA-seq 确定了与小鼠子宫容受性相关的转录变化,但由于子宫是由多种细胞类型组成的复杂器官,因此数据价值有限。在这里,我们旨在以单细胞分辨率破译小鼠子宫对胚胎植入的接受性。
更新日期:2021-11-03
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