The prolonged intake of the artificial sweetener aspartame is known to have deleterious effects. Our biophysical experimentations indicate that aspartame forms self-assembled cytotoxic fibrillar etiologies that affect the intrinsic integrity of the phospholipid membrane bilayer through electrostatic interaction and hydrophobic insertion, thereby making the membrane less rigid and more heterogeneous.

中文翻译：

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人工甜味剂阿斯巴甜的自组装对磷脂膜产生不利影响：其有害影响的合理原因

众所周知，长期摄入人工甜味剂阿斯巴甜会产生有害影响。我们的生物物理实验表明，阿斯巴甜形成自组装的细胞毒性纤维状病因，通过静电相互作用和疏水性插入影响磷脂膜双层的内在完整性，从而使膜的刚性降低且异质性更强。