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Erratum
The FASEB Journal ( IF 4.8 ) Pub Date : 2021-09-22 , DOI: 10.1096/fsb2.21954


Correction for “Degradation of endothelial glycocalyx in Tanzanian children with falciparum malaria,” by Margaret A. Bush, Salvatore M. Florence, Tsin W. Yeo, Ayam R. Kalingonji, Youwei Chen, Donald L. Granger, Matthew P. Rubach, Nicholas M. Anstey, Esther D. Mwaikambo, and Joe Brice Weinberg, which was first published August 17, 2021; 10.1096/fj.202100277R (FASEB J. 35, e21805).

The authors report that there are composition errors (a spelling error and missing P values) in the Table 2 footnotes in the published article. The corrected Table 2 is as follows:

TABLE 2. Baseline hematology, biochemical and tissue oxygen saturationa a Median (range), except when indicated otherwise.
Parameter Healthy control (n = 60) Moderately severe malaria (n = 44) Severe malaria (n = 42) P valueb b ANOVA or Kruskal-Wallis test for comparison of healthy control, moderately severe malaria (MSM) and severe malaria (SM) groups. Significant difference between SM and MSM groups.
WBC (×109 cells/L) 7.1 (3.0-13.0) 7.4 (4.3-17.3) 8.0 (2.3-27.2) .198
Hemoglobin, g/dL 11.8 (8.7-13.8) 9.5 (6.1-15.1) 8.4 (4.5-11.9)c c Hemoglobin, P < .001 MSM vs. SM.
<.001
Platelets (×109 cells/L) 352.5 (98.0-542.0) 134.5 (22.0-488.0) 91.0 (13.0-329.0) <.001
Lactate (mM) 2.3 (0.8-4.1) 3.1 (1.5-5.1) 4.1 (0.02-15.0) <.001
(n = 30) (n = 27) (n = 30)
Creatinine (serum; mg/dL) 0.4 (0.2-0.6) 0.3 (0.2-0.4) 0.3 (0.2-0.5) .056
(n = 20) (n = 18) (n = 19)
Parasite density (# per µL; geometric mean, 95% confidence interval) 0 107,640 (86,747-133,565) 155,718 (112,205-216105) .015d d Parasitemia (by Mann-Whitney), P = .015 MSM vs. SM.
HRP-2 (ng/mL) 0.01 (0.01-0.04) 39.1 (0.01-1317) 60.9 (3.06-1625) <.001
Urinary GAG (g/mol Cr) 4.24 (0.04-12.46) 10.18 (0.35-83.73.) 13.77 (4.01-25.96) <.001
Plasma syndecan-1 (ng/mL) 65.0 (22.80-276.3) 235.3 (20.70-899.4) 273.7 (35.0-1558.0) <.001
Plasma angiopoietin-2 (pg/mL) 1605 (806-6290) 3447 (1256-16021) 4612 (2186-30491) <.001
StO2, at baseline (%) 80 (55-93) 75 (49-93) 79 (50-94) .055
StO2 low, at end of occlusion (%) 39 (13-62) 37 (0-73) 50 (4-84)e e Oxygen saturation measures, P < .05 MSM vs. SM.
.035
Recovery StO2 % increase/sec 1.42 (−0.02-4.17) 1.20 (0.03-5.96) 0.61 (0.01-2.55)e e Oxygen saturation measures, P < .05 MSM vs. SM.
.005
Peak StO2 after release % 90 (59-98) 86 (61-96) 87 (55-97) .116
Difference between peak and baseline StO2% 8.2 (−4.4-26.9) 10.9 (0.8-35) 7.8 (−11.7-26.0) .045
O2 consumption (VO2) 170 (13-245) 132 (45-286) 122 (26-276) .043
Tissue Hb index at baseline 11.4 (5-14.1) 10.8 (4.9-15.1) 10.9 (6.0-18.7) .425
Tissue Hb index, end of occlusion 7.2 (3.3-11.65) 7.2 (3.5-13.6) 7.6 (3.2-13.0) .294
  • Abbreviations: HRP-2, histidine rich protein-2; StO2, tissue oxygen saturation.
  • a Median (range), except when indicated otherwise.
  • b ANOVA or Kruskal-Wallis test for comparison of healthy control, moderately severe malaria (MSM) and severe malaria (SM) groups. Significant difference between SM and MSM groups.
  • c Hemoglobin, P < .001 MSM vs. SM.
  • d Parasitemia (by Mann-Whitney), P = .015 MSM vs. SM.
  • e Oxygen saturation measures, P < .05 MSM vs. SM.


中文翻译:

勘误表

更正“坦桑尼亚恶性疟儿童内皮糖萼的降解”,作者:Margaret A. Bush、Salvatore M. Florence、Tsin W. Yeo、Ayam R. Kalingonji、Youwei Chen、Donald L. Granger、Matthew P. Rubach、Nicholas M. Anstey、Esther D. Mwaikambo 和 Joe Brice Weinberg,于 2021 年 8 月 17 日首次出版;10.1096 / fj.202100277R(FASEBĴ35,e21805)。

作者报告说,已发表文章的表 2 脚注中存在构成错误(拼写错误和P值缺失)。修正后的表2如下:

表 2.基线血液学、生化和组织氧饱和度a a 中位数(范围),除非另有说明。
范围 健康对照(n = 60) 中度严重疟疾(n = 44) 严重疟疾(n = 42) Pb b 用于比较健康对照组、中重度疟疾 (MSM) 和重度疟疾 (SM) 组的方差分析或 Kruskal-Wallis 检验。SM 和 MSM 组之间的显着差异。
白细胞(×10 9 个细胞/升) 7.1 (3.0-13.0) 7.4 (4.3-17.3) 8.0 (2.3-27.2) .198
血红蛋白,g/dL 11.8 (8.7-13.8) 9.5 (6.1-15.1) 8.4 (4.5-11.9) c c 血红蛋白, P  < .001 MSM 与 SM。
<.001
血小板(×10 9 个细胞/L) 352.5 (98.0-542.0) 134.5 (22.0-488.0) 91.0 (13.0-329.0) <.001
乳酸 (mM) 2.3 (0.8-4.1) 3.1 (1.5-5.1) 4.1 (0.02-15.0) <.001
(n = 30) (n = 27) (n = 30)
肌酐(血清;mg/dL) 0.4 (0.2-0.6) 0.3 (0.2-0.4) 0.3 (0.2-0.5) .056
(n = 20) (n = 18) (n = 19)
寄生虫密度(每微升 #;几何平均值,95% 置信区间) 0 107,640 (86,747-133,565) 155,718 (112,205-216105) .015 d 寄生虫血症(由 Mann-Whitney 提供), P = .015 MSM 与 SM。
HRP-2 (ng/mL) 0.01 (0.01-0.04) 39.1 (0.01-1317) 60.9 (3.06-1625) <.001
尿 GAG (g/mol Cr) 4.24 (0.04-12.46) 10.18 (0.35-83.73。) 13.77 (4.01-25.96) <.001
血浆 syndecan-1 (ng/mL) 65.0 (22.80-276.3) 235.3 (20.70-899.4) 273.7 (35.0-1558.0) <.001
血浆血管生成素-2 (pg/mL) 1605 (806-6290) 3447 (1256-16021) 4612 (2186-30491) <.001
StO2,在基线 (%) 80 (55-93) 75 (49-93) 79 (50-94) .055
StO2 低,闭塞结束时 (%) 39 (13-62) 37 (0-73) 50 (4-84) e e 氧饱和度测量值, P < .05 MSM 与 SM。
.035
恢复 StO2 % 增加/秒 1.42 (-0.02-4.17) 1.20 (0.03-5.96) 0.61 (0.01-2.55) e e 氧饱和度测量值, P < .05 MSM 与 SM。
.005
释放后的峰值 StO2 % 90 (59-98) 86 (61-96) 87 (55-97) .116
峰和基线之间的差异 StO2% 8.2 (-4.4-26.9) 10.9 (0.8-35) 7.8 (-11.7-26.0) .045
O 2消耗量 (VO 2 ) 170 (13-245) 132 (45-286) 122 (26-276) .043
基线时的组织 Hb 指数 11.4 (5-14.1) 10.8 (4.9-15.1) 10.9 (6.0-18.7) .425
组织 Hb 指数,闭塞结束 7.2 (3.3-11.65) 7.2 (3.5-13.6) 7.6 (3.2-13.0) .294
  • 缩写:HRP-2,富含组氨酸的蛋白质-2;StO2,组织氧饱和度。
  • a 中位数(范围),除非另有说明。
  • b 用于比较健康对照组、中重度疟疾 (MSM) 和重度疟疾 (SM) 组的方差分析或 Kruskal-Wallis 检验。SM 和 MSM 组之间的显着差异。
  • c 血红蛋白, P  < .001 MSM 与 SM。
  • d 寄生虫血症(由 Mann-Whitney 提供), P = .015 MSM 与 SM。
  • e 氧饱和度测量值, P < .05 MSM 与 SM。
更新日期:2021-09-23
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