3-Aminobenzoate based N,N and N,O coordinated Ru^II complexes of various aldehydes show imidazole based N,N coordinated complexes are more stable and better cytotoxic against the TNBC, MDA-MB-231 (eight times more toxic than oxaliplatin), in comparison to the N,O coordinated ones. DNA is one of the targets to kill via apoptosis although the alteration of the aldehyde varies the cell cycle arrest from G0/G1 to G2/M.

中文翻译：

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3-氨基苯甲酸席夫碱的N,N和N,O-配位RuII配合物的合成、结构和细胞毒性抗三阴性乳腺癌

3-氨基苯甲酸酯基 N , N 和 N , O 各种醛的配位Ru ^II配合物显示咪唑基N , N配位配合物对 TNBC, MDA-MB-231 (毒性比奥沙利铂高 8 倍)更稳定和更好的细胞毒性,与N , O协调的相比。DNA 是通过细胞凋亡杀死的目标之一，尽管醛的改变会导致细胞周期停滞从 G0/G1 到 G2/M。