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Symbiosis and Dysbiosis of the Human Mycobiome
Frontiers in Microbiology ( IF 5.2 ) Pub Date : 2021-09-22 , DOI: 10.3389/fmicb.2021.636131
Kirtishri Mishra 1, 2 , Laura Bukavina 1, 2 , Mahmoud Ghannoum 2, 3, 4
Affiliation  

The influence of microbiological species has gained increased visibility and traction in the medical domain with major revelations about the role of bacteria on symbiosis and dysbiosis. A large reason for these revelations can be attributed to advances in deep-sequencing technologies. However, the research on the role of fungi has lagged. With the continued utilization of sequencing technologies in conjunction with traditional culture assays, we have the opportunity to shed light on the complex interplay between the bacteriome and the mycobiome as they relate to human health. In this review, we aim to offer a comprehensive overview of the human mycobiome in healthy and diseased states in a systematic way. The authors hope that the reader will utilize this review as a scaffolding to formulate their understanding of the mycobiome and pursue further research.



中文翻译:

人类真菌群的共生与失调

随着关于细菌在共生和生态失调中的作用的重大发现,微生物物种的影响在医学领域获得了越来越多的知名度和吸引力。这些启示的一个重要原因可归因于深度测序技术的进步。然而,关于真菌作用的研究却滞后。随着测序技术与传统培养分析的不断结合,我们有机会阐明细菌组和真菌组之间复杂的相互作用,因为它们与人类健康有关。在这篇综述中,我们旨在以系统的方式全面概述健康和疾病状态下的人类真菌群。

更新日期:2021-09-22
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