Substituted undecahydrido-closo-dodecaborates [B₁₂H₁₁NR₂]²⁻ have potential use in materials and drugs, but have presented a synthetic challenge. Microwave-assisted palladium-catalyzed amination of iodo-dodecaborate [B₁₂H₁₁I]²⁻ allows mild and reproducible formation of B–N bonds with aromatic amines, HN-containing heteroaromatics, and amides. The reaction allows general access to amides, reproducible reactions to dodecaborate-substituted anilines, and, for the first time, the substitution of dodecaborate with HN-containing heterocycles.

中文翻译：

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通过钯催化、微波辅助的氮化合物与碘-十二硼酸盐交叉偶联形成 B-N 键

取代undecahydrido-闭合碳-dodecaborates [B ₁₂ ħ ₁₁ NR ₂ ] ^2-具有在材料和药物的潜在用途，但已经提出了一种合成的挑战。微波辅助钯催化的碘十二硼酸盐 [B ₁₂ H ₁₁ I] ^2-胺化允许与芳香胺、含 HN 的杂芳烃和酰胺温和且可重复地形成 B-N 键。该反应允许一般访问酰胺，可重现反应以十二硼酸盐取代的苯胺，并首次用含 HN 的杂环取代十二硼酸盐。