The development of an accurate, sensitive and selective sensor for the detection of bisphenol A (BPA) based on the incorporation of a new phthalocyanine derivative, cobalt phthalocyanine, C,C,C,C-tetracarboxylic acid-polyacrylamide (CoPc-PAA) into a carbon-paste matrix is presented using voltammetry and constant potential techniques. The influence of measuring parameters such as pH and scan rate on the analytical performance of the sensor was evaluated. Several kinetic parameters such as electron transfer number (n), charge transfer coefficient (α), electrode surface area (A) and diffusion coefficient (D) were also calculated. Under optimum conditions, particularly at pH 7.2, the BPA sensor resulted in a wide linear range from 25 × 10⁻¹¹ M to 2.5 × 10⁻⁷ M and a limit of detection as low as 63.5 pM. Based on these findings, it can be concluded that our sensor can be substantially utilized for detecting BPA in spiked milk samples.

中文翻译：

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基于钴酞菁修饰碳糊电极的高灵敏度和选择性双酚A传感器的开发：在乳制品分析中的应用

基于将新型酞菁衍生物钴酞菁、C、C、C、C-四羧酸-聚丙烯酰胺 (CoPc-PAA) 加入到双酚 A (BPA) 中，开发了一种用于检测双酚 A (BPA) 的准确、灵敏和选择性传感器使用伏安法和恒电位技术呈现碳糊基质。评估了测量参数（如 pH 值和扫描速率）对传感器分析性能的影响。几个动力学参数，如电子转移数 ( n )、电荷转移系数 ( α )、电极表面积 ( A ) 和扩散系数 ( D)) 也进行了计算。在最佳条件下，特别是在 pH 7.2 时，BPA 传感器产生从 25 × 10 ^-11 M 到 2.5 × 10 ^-7 M的宽线性范围和低至 63.5 pM 的检测限。基于这些发现，可以得出结论，我们的传感器可充分用于检测加标牛奶样品中的 BPA。