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Effect of chlorhexidine gluconate on mechanical and anti-microbial properties of thermoplastic cassava starch
Carbohydrate Polymers ( IF 11.2 ) Pub Date : 2021-09-22 , DOI: 10.1016/j.carbpol.2021.118690
Nanthicha Thajai 1 , Kittisak Jantanasakulwong 2 , Pornchai Rachtanapun 2 , Pensak Jantrawut 3 , Krittameth Kiattipornpithak 4 , Thidarat Kanthiya 4 , Winita Punyodom 5
Affiliation  

Antimicrobial thermoplastic starch (TPS) was developed using cassava starch, glycerol, and chlorhexidine gluconate (CHG) blend. CHG was added at concentrations of 1%, 5%, 10%, and 20% (wt./wt.) as an antimicrobial additive. The tensile strength and hardness of the blended samples increased with the chlorhexidine gluconate content, especially for 1% CHG. wt./wt. (12.6 MPa and 94, respectively). The TPS/CHG20 blend exhibited a large phase of CHG and recrystallization of TPS. The water solubility decreased with the addition of CHG. Nuclear magnetic resonance data confirmed a reaction between the hydroxyl groups of TPS and the amino groups of CHG. The TPS/CHG20% exhibited an inhibition zone for three bacterial types (Staphylococcus aureus, Escherichia coli, and Bacillus cereus) and three fungal types (Rhizopus oligosporus, Aspergillus oryzae, and Candida albicans). CHG acted simultaneously as a chain extender and an antimicrobial additive for TPS, improving its tensile strength, hardness, and anti-microbial properties.



中文翻译:

葡萄糖酸氯己定对热塑性木薯淀粉力学和抗菌性能的影响

抗菌热塑性淀粉 (TPS) 是使用木薯淀粉、甘油和葡萄糖酸氯己定 (CHG) 混合物开发的。以 1%、5%、10% 和 20% (wt./wt.) 的浓度添加 CHG 作为抗微生物添加剂。混合样品的拉伸强度和硬度随着葡萄糖酸氯己定含量的增加而增加,特别是对于 1% CHG。重量/重量 (分别为 12.6 MPa 和 94)。TPS/CHG20 共混物表现出大量的 CHG 相和 TPS 的再结晶。水溶性随着CHG的加入而降低。核磁共振数据证实了 TPS 的羟基和 CHG 的氨基之间的反应。TPS/CHG20% 对三种细菌类型(金黄色葡萄球菌大肠杆菌蜡状芽孢杆菌)和三种真菌类型(少孢根霉米曲霉白色念珠菌)。CHG 同时作为 TPS 的扩链剂和抗菌添加剂,提高其拉伸强度、硬度和抗菌性能。

更新日期:2021-10-06
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