The development of science and technology has deepened people's understanding of cancer, changing the management of malignant tumors in the medical field. Given the common precancerous characteristics of colorectal cancer (CRC), researchers studied early CRC screening. The complexity of traditional diagnostics forced medical staff to speed up CRC innovation early screening methods. Here, we prepared nano-colloidal gold raw materials with different particle sizes (15 and 30 nm) and observed the morphological characteristics and properties of the materials. Simultaneously, the nanocolloidal gold double antibody sandwich kit was designed through the optimum pH value and protein content screening experiment. The results of clinical enteroscopy confirmed the important guiding significance of the equipment in early CRC screening.

中文翻译：

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基于纳米胶体金夹心免疫层析法的大肠癌隐血早期诊断。

科学技术的发展加深了人们对癌症的认识，改变了医学领域对恶性肿瘤的管理。鉴于结直肠癌 (CRC) 的常见癌前特征，研究人员研究了早期 CRC 筛查。传统诊断的复杂性迫使医务人员加快 CRC 早期筛查方法的创新。在这里，我们制备了不同粒径（15 和 30 nm）的纳米胶体金原料，并观察了材料的形态特征和性能。同时，通过最适pH值和蛋白质含量筛选实验设计了纳米胶体金双抗体夹心试剂盒。临床小肠镜检查结果证实了该设备在CRC早期筛查中的重要指导意义。