Mosses are mainly the object of ecological and taxonomic research. This group of plants are still underestimated by scientists in other aspects of research. Recent research has shown that these plants contain remarkable and unique substances with high biological activity. Five species of mosses from a large urban ecosystem were identified for present study. In order to determine their biological potential, multifaceted studies were carried out, including: total phenolics content, antioxidant activity, antimicrobial and antifungal study, cytotoxicity evaluation, and scratch assay to assess pro-regenerative effect in the context of their possible use as the ingredients of biologically active cosmetics. Additionally, determination of individual phenolic compounds in selected extracts of the tested mosses was made. Research showed that Ceratodon purpureus and Dryptodon pulvinatus extracts had the greatest potential as antioxidants and antimicrobial activity. The cytotoxicity assessment indicated that the extracts from Dryptodon pulvinatus and Rhytidiadelphus squarossus exerted the strongest negative effect on mouse fibroblast line L929 viability at higher concentrations. While, the extract from Tortulla muralis best stimulated human foreskin fibroblast line HFF-1 proliferation and wound healing. The research on individual phenolic compounds content in the extracts tested indicated over 20 peaks on UPLC chromatograms. The conducted study has shown that mosses, especially so far unexplored species of open ecosystems, and e.g. epilytic habitats, may be a valuable source of biologically active substances and thus may constitute important medical and cosmetic possibilities.

中文翻译：

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从开放栖息地获得的苔藓的细胞毒性、抗菌和抗氧化活性。

苔藓主要是生态学和分类学研究的对象。这组植物在其他方面的研究中仍被科学家低估。最近的研究表明，这些植物含有具有高生物活性的非凡而独特的物质。本研究确定了来自大型城市生态系统的五种苔藓。为了确定它们的生物学潜力，进行了多方面的研究，包括：总酚含量、抗氧化活性、抗菌和抗真菌研究、细胞毒性评估和划痕试验，以评估在它们可能用作成分的背景下的促再生作用生物活性化妆品。此外，还对选定的受试苔藓提取物中的各个酚类化合物进行了测定。研究表明，Ceratodon purpureus 和 Dryptodon pulvinatus 提取物作为抗氧化剂和抗菌活性的潜力最大。细胞毒性评估表明，在较高浓度下，Dryptodon pulvinatus 和 Rhytidiadelphus squaressus 的提取物对小鼠成纤维细胞系 L929 的生存能力产生最强的负面影响。同时，来自 Tortulla muralis 的提取物最能刺激人包皮成纤维细胞系 HFF-1 增殖和伤口愈合。对所测试提取物中个别酚类化合物含量的研究表明，UPLC 色谱图上有 20 多个峰。进行的研究表明，苔藓，尤其是迄今为止尚未开发的开放生态系统物种，例如外生栖息地，