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Trends and challenges of nanotechnology in self-test at home
Trends in Analytical Chemistry ( IF 13.1 ) Pub Date : 2021-09-21 , DOI: 10.1016/j.trac.2021.116438
Huifang Liu , Thuy Nguyen Thi Dao , Bonhan Koo , Yoon Ok Jang , Yong Shin

Recently, the development of nanotechnology (NTC) has been considered as a promising revolution in designing and fabricating biomedical systems with applications for point-of-care tests (POCTs), smartphone technology, and wearable electronics for self-testing. Although many new devices have been introduced, there is still a need for rapid and accurate self-test kits. We summarize the recent progress in NTC toward POCT devices for self-diagnosis of disease. This review focuses on the potential application of self-test devices and the possible technologies that would support their development, differentiating this review from the plethora of reviews on progress in POCT. Furthermore, we review how NTC has been implemented for designing and deploying devices capable of NTC-related self-sampling and self-diagnosis with naked-eye readable systems as user-friendly, at-home tests. Future perspectives on integrated and automated micro-/nano-sampling detection systems compatible with mobile/hand-held and wearable devices for improved management of communicable and non-communicable diseases are discussed.



中文翻译:

纳米技术在家庭自测中的趋势与挑战

最近,纳米技术 (NTC) 的发展被认为是设计和制造生物医学系统的一场有希望的革命,该系统适用于即时测试 (POCT)、智能手机技术和用于自我测试的可穿戴电子设备。尽管已经推出了许多新设备,但仍然需要快速准确的自检套件。我们总结了 NTC 在用于疾病自我诊断的 POCT 设备方面的最新进展。本次审查侧重于自测设备的潜在应用以及支持其开发的可能技术,将本次审查与大量关于 POCT 进展的审查区分开来。此外,我们回顾了如何实施 NTC 来设计和部署能够使用裸眼可读系统进行 NTC 相关自采样和自诊断的设备,作为用户友好的家庭测试。讨论了与移动/手持和可穿戴设备兼容的集成和自动化微/纳米采样检测系统的未来前景,以改进对传染性和非传染性疾病的管理。

更新日期:2021-09-29
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