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The natural stilbenoid (–)-hopeaphenol inhibits cellular entry of SARS-CoV-2 USA-WA1/2020, B.1.1.7 and B.1.351 variants
Antimicrobial Agents and Chemotherapy ( IF 4.9 ) Pub Date : 2021-09-20 , DOI: 10.1128/aac.00772-21
Ian Tietjen 1 , Joel Cassel 1 , Emery T Register 1 , Xiang Yang Zhou 1 , Troy E Messick 1 , Frederick Keeney 1 , Lily D Lu 1 , Karren D Beattie 2 , Topul Rali 3 , Pablo Tebas 4 , Hildegund C J Ertl 1 , Joseph M Salvino 1 , Rohan A Davis 2 , Luis J Montaner 1
Affiliation  

Antivirals are urgently needed to combat the global SARS-CoV-2/COVID-19 pandemic, supplement existing vaccine efforts, and target emerging SARS-CoV-2 variants of concern. Small molecules that interfere with binding of the viral spike receptor binding ...

中文翻译:

天然二苯乙烯 (-)-希望苯酚抑制 SARS-CoV-2 USA-WA1/2020、B.1.1.7 和 B.1.351 变种的细胞进入

迫切需要抗病毒药物来对抗全球 SARS-CoV-2/COVID-19 大流行,补充现有的疫苗工作,并针对新出现的 SARS-CoV-2 变种。干扰病毒刺突受体结合的小分子...
更新日期:2021-09-21
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