ABSTRACT

Objective

The aim of this study was to investigate cases with ocular complications associated with intravesical BCG therapy in terms of clinical features, demographic features and type of ocular involvement.

Methods

PubMed database was scanned for relevant publications using the keywords. Thirty-seven publications and 147 reported cases were identified related to the development of ocular complications due to intravesical BCG treatment.

Results

As a result of the analysis performed according to eye involvement, there were 17 cases of conjunctivitis, 7 uveitis, and 5 endophthalmitis. Only 27 (18.3%) cases were of primary ocular involvement and Reiter's syndrome was present in 120 (81.6%) of all cases.

Conclusions

Most of the side-effects of BCG therapy are minor and of short duration. Although rare, it has been reported that potentially serious ocular complications can develop after treatment. Physicians must keep these facts in mind and be alert to the development of ocular symptoms following BCG therapy.

中文翻译：

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使用池分析法评估卡介苗 (BCG) 治疗引起的眼部并发症病例

摘要

客观的

本研究的目的是调查与膀胱内 BCG 治疗相关的眼部并发症的临床特征、人口统计学特征和眼部受累类型。

方法

使用关键字扫描 PubMed 数据库以查找相关出版物。确定了 37 篇出版物和 147 例报告病例与膀胱内卡介苗治疗引起的眼部并发症有关。

结果

根据眼睛受累情况进行分析，结膜炎17例，葡萄膜炎7例，眼内炎5例。只有 27 例 (18.3%) 病例是原发性眼部受累，所有病例中有 120 例 (81.6%) 存在 Reiter 综合征。

结论

BCG 治疗的大多数副作用都很轻微且持续时间短。尽管很少见，但据报道，治疗后可能会出现潜在的严重眼部并发症。医生必须牢记这些事实，并警惕 BCG 治疗后眼部症状的发展。