Janus structure can stabilize oil/water interface and improve interfacial mass transfer in biphasic systems due to its asymmetric wettability and multifunctionality of its dual compartment structure. However, the fabrication of novel Janus structures with resistance to complex application environments is still a challenge due to the difficulty in finding suitable and durable building blocks and connecting them into Janus structures with asymmetric wettability. Herein, Janus carbon-mesoporous silica particles (CMS), featuring a joint of spherical carbon and cubic periodic mesoporous organosilica (PMO), have been fabricated via a facile anisotropic growth. The spacial isolation of hydrophobic carbon domain and hydrophilic PMO domain endows the particle with asymmetric wettability to stabilize emulsion with large droplet size (up to 1.5 mm). The Pickering emulsions emulsified by CMS exhibit high interfacial, thermal and salt stability. Besides, by loading phosphotungstic acid on PMO part, the CMS exhibit a yield of 94% of cinnamaldehyde glycol acetal in biphasic reaction. Furthermore，the CMS have great potential of being a versatile platform not only for catalytic reactions but also for interfacial oriented energy storage, battery, sensing, and biomedical imaging.

由于其双隔室结构的不对称润湿性和多功能性，Janus 结构可以稳定油/水界面并改善双相系统中的界面传质。然而，由于难以找到合适且耐用的构建块并将它们连接成具有不对称润湿性的 Janus 结构，因此制造具有抵抗复杂应用环境的新型 Janus 结构仍然是一个挑战。在此，Janus 碳介孔二氧化硅颗粒 (CMS) 具有球形碳和立方周期性介孔有机二氧化硅 (PMO) 的结合，已通过简单的各向异性生长制造。疏水碳域和亲水 PMO 域的空间隔离赋予颗粒不对称润湿性，以稳定具有大液滴尺寸（高达 1.5 毫米）的乳液。由 CMS 乳化的 Pickering 乳液表现出很高的界面、热和盐稳定性。此外，通过在 PMO 部分负载磷钨酸，CMS 在双相反应中表现出 94% 的肉桂醛乙二醇缩醛收率。此外，CMS 具有巨大的潜力，不仅可以作为催化反应的通用平台，还可以用于界面定向储能、电池、传感和生物医学成像。