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Two New Aporphine Alkaloids from Amoora cucullata and their Antibacterial Activity
Chemistry of Natural Compounds ( IF 0.8 ) Pub Date : 2021-09-20 , DOI: 10.1007/s10600-021-03508-6
Parinuch Chumkaew 1 , Passakorn Teerapongpisan 1 , Jaraslak Pechwang 1
Affiliation  

Two new aporphine alkaloids, amocurines D and E (1 and 2), together with five known compounds (3–7), were isolated from the stems of Amoora cucullata. The structures of these compounds were elucidated based on their spectroscopic data. Compound 1 showed significant activities against Staphylococcus aureus (ATCC25923) and Bacillus subtilis (ATCC6633) with MIC value of 3.1 μg/mL, whereas 2 exhibited selective antibacterial activity against B. subtilis.



中文翻译:

Amoora cucullata 中两种新的阿朴啡生物碱及其抗菌活性

Amoora cucullata的茎中分离出两种新的阿朴啡生物碱,即 amocurines D 和 E(12)以及五种已知化合物(3-7基于它们的光谱数据阐明了这些化合物的结构。化合物1表现出抗显著活动金黄色葡萄球菌(ATCC25923)和枯草芽孢杆菌(ATCC6633)具有MIC的3.1值μ克/毫升,而2对显示出选择性抗菌活性的枯草芽孢杆菌。

更新日期:2021-09-21
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