A lithium-bromide-promoted nucleophilic substitution/annulation cascade reaction between CF₃-imidoyl sulfoxonium ylides and 1,3-dicarbonyl compounds has been established, and the corresponding 1,2,3-trisubstituted 5-trifluoromethylpyrroles have been obtained in 27–78% yield. This reaction features a broad substrate scope and generates dimethyl sulfoxide and H₂O as byproducts.

中文翻译：

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CF3–Imidoyl Sulfoxonium Ylides 与 1,3-二羰基化合物的环化：获得 1,2,3-三取代的 5-三氟甲基吡咯

已经建立了溴化锂促进的 CF _{3 -}亚氨酰基锍叶立德与 1,3-二羰基化合物之间的亲核取代/环化级联反应，并在 27-78 年获得了相应的 1,2,3-三取代 5-三氟甲基吡咯％ 屈服。该反应具有广泛的底物范围，并生成二甲基亚砜和 H ₂ O 作为副产物。