Metabolic networks support cancer cell survival, proliferation, and malignant progression. Cancer cells take up large amounts of nutrients such as glucose and glutamine whose metabolism provides the energy, reducing equivalents, and biosynthetic precursors required to meet the biosynthetic demands of proliferation. Intermediates of glycolysis and the tricarboxylic acid (TCA) cycle provide critical building blocks for synthesis of non-essential amino acids, nucleotides, and fatty acids. To view this SnapShot, open or download the PDF.

中文翻译：

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快照：癌症代谢

代谢网络支持癌细胞存活、增殖和恶性进展。癌细胞吸收大量的营养物质，如葡萄糖和谷氨酰胺，它们的代谢提供能量、还原当量和满足增殖生物合成需求所需的生物合成前体。糖酵解和三羧酸 (TCA) 循环的中间体为非必需氨基酸、核苷酸和脂肪酸的合成提供了关键构件。要查看此快照，请打开或下载 PDF。