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Enantioselective Construction of Modular and Asymmetric Baskets
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2021-09-20 , DOI: 10.1002/anie.202110849
Michael J Gunther 1 , Radoslav Z Pavlović 1 , Tyler J Finnegan 1 , Xiuze Wang 1 , Jovica D Badjić 1
Affiliation  

A stepwise Suzuki–Miyaura coupling of custom-built A, B, and C building blocks gives ABC baskets. Such enantioselective and modular construction allows choosing depth and shape of the cavitand's nonpolar pocket while also selecting desired functional groups at the rim. Building more effective mimics of biological receptors and catalysts is within reach.
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中文翻译:

模块化和不对称篮子的对映选择性构造

定制的ABC构建块的逐步 Suzuki-Miyaura 耦合提供了ABC篮子。这种对映选择性和模块化结构允许选择腔体非极性袋的深度和形状,同时还可以在边缘选择所需的官能团。建立更有效的生物受体和催化剂模拟物是触手可及的。
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更新日期:2021-11-08
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