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Inflammatory Biomarkers and Components of Metabolic Syndrome in Adolescents: a Systematic Review
Inflammation ( IF 5.1 ) Pub Date : 2021-09-21 , DOI: 10.1007/s10753-021-01549-1
Ariane R de F Rocha 1 , Núbia de S Morais 1 , Silvia E Priore 2 , Sylvia do C C Franceschini 2
Affiliation  

Metabolic syndrome (MetS) has been prevalent among adolescents. The association between the concentration of inflammatory markers and the individual components of the metabolic syndrome indicates that inflammation, when there is no recent or ongoing disease, mediated by an inflammatory process, is an event that may precede the development of metabolic disorders in teenagers. The objective of this study is to verify the association of inflammatory biomarkers with the components of metabolic syndrome in adolescents. From a search of 3 databases, 13 articles met the study inclusion criteria. Two investigators independently extracted data from included studies. The evaluated inflammatory biomarkers are related to the components of MetS (insulin resistance, central and visceral obesity, arterial hypertension, dyslipidemia), which may increase the risk of developing the syndrome in adolescents. The results of this review are of clinical relevance, since the evaluation of inflammatory biomarkers in the presence of metabolic alterations can help to identify the risk factors that lead to the progression of MetS in adolescents.



中文翻译:

青少年代谢综合征的炎症生物标志物和成分:系统评价

代谢综合征(MetS)在青少年中普遍存在。炎症标志物的浓度与代谢综合征的各个成分之间的关​​联表明,当没有由炎症过程介导的近期或持续疾病时,炎症是可能在青少年代谢紊乱发展之前发生的事件。本研究的目的是验证炎症生物标志物与青少年代谢综合征成分的关联。通过对 3 个数据库的搜索,有 13 篇文章符合研究纳入标准。两名研究者独立地从纳入研究中提取数据。评估的炎症生物标志物与 MetS 的成分(胰岛素抵抗、中枢性和内脏性肥胖、动脉高血压、血脂异常)有关,这可能会增加青少年患该综合征的风险。本综述的结果具有临床相关性,因为在存在代谢改变的情况下评估炎症生物标志物有助于确定导致青少年 MetS 进展的风险因素。

更新日期:2021-09-21
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