Among zwitterionic structures, the choline phosphate (CP) group is uniquely attractive for its ability to access novel chemical compositions that embed functional groups directly into the zwitterionic moiety. This paper describes the attachment of fluorinated alkyl groups to CP moieties, yielding zwitterionic monomers 1 and 2 that proved amenable to controlled free radical polymerization and the production of a new set of CP-containing fluorinated polymers and copolymers with phosphorylcholine (PC) zwitterions. This combination of fluorinated hydrocarbons and zwitterions affords novel, water-soluble polymeric amphiphiles that we have examined at fluid interfaces, as coatings, in cell culture, and in magnetic resonance imaging.

中文翻译：

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氟化聚合物两性离子：磷酸胆碱和磷酸胆碱

在两性离子结构中，磷酸胆碱 (CP) 基团因其能够获得将官能团直接嵌入两性离子部分的新型化学成分而具有独特的吸引力。本文描述了氟化烷基与 CP 部分的连接，产生了两性离子单体1和2 ，这些单体 1 和 2被证明可以进行受控的自由基聚合，以及生产一组新的含 CP 的氟化聚合物和具有磷酰胆碱 (PC) 两性离子的共聚物。氟化烃和两性离子的这种组合提供了我们在流体界面、涂层、细胞培养和磁共振成像中检测过的新型水溶性聚合物两亲物。