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Preparation, characterization, and application of polysaccharide-based emulsions incorporated with lavender essential oil for skin-friendly cellulosic support
International Journal of Biological Macromolecules ( IF 8.2 ) Pub Date : 2021-09-20 , DOI: 10.1016/j.ijbiomac.2021.09.090
Angela Danila 1 , Emil Ioan Muresan 2 , Sorin-Alexandru Ibanescu 3 , Alina Popescu 4 , Maricel Danu 5 , Carmen Zaharia 2 , Gizem Ceylan Türkoğlu 6 , Gökhan Erkan 6 , Adela-Ioana Staras 7
Affiliation  

This study aimed to develop polysaccharide-based emulsions incorporated with lavender essential oil and their application on cellulosic support for patches obtaining. The lavender essential oil has been added to emulsions as an active compound mainly due to its antimicrobial properties. In this study, emulsions were used to deliver active ingredients (lavender essential oil). The chemical composition of essential oil was analyzed using gas chromatography–mass spectrometry (GC/MS). A total of seven emulsions (RiACL) were evaluated by determining rheological parameters and microbiological analysis. One of the emulsions (R7ACL) was applied to cellulosic support to obtain non-irritating textiles with controlled release of the active compound and moisturizing effects. Obtained cellulosic support was analyzed in terms of active compound controlled release, toxicity and antimicrobial testing, and skin analysis in healthy volunteers. It was found that the cellulosic supports treated with O/W emulsions are non-irritating, have softness and moisturizing effects, and can be used safely in topical applications for patches obtaining.



中文翻译:

与薰衣草精油混合的多糖基乳液的制备、表征和应用,用于对皮肤友好的纤维素支持

本研究旨在开发掺入薰衣草精油的多糖基乳液及其在获得贴片的纤维素支持上的应用。薰衣草精油已作为活性化合物添加到乳液中,主要是由于其抗菌特性。在这项研究中,乳液用于提供活性成分(薰衣草精油)。使用气相色谱-质谱(GC/MS)分析精油的化学成分。通过确定流变参数和微生物分析,总共评估了七种乳液 (RiACL)。其中一种乳液 (R7ACL) 用于纤维素载体,以获得具有活性化合物受控释放和保湿效果的无刺激性纺织品。在健康志愿者的活性化合物控释、毒性和抗菌测试以及皮肤分析方面对获得的纤维素支持进行了分析。发现用O/W乳液处理的纤维素载体无刺激性,具有柔软和保湿效果,并且可以安全地用于局部应用以获得贴剂。

更新日期:2021-09-24
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