当前位置: X-MOL 学术Int. Dairy J. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Antioxidant, antimicrobial and anticarcinogenic activities of bovine milk proteins and their hydrolysates - A review
International Dairy Journal ( IF 3.1 ) Pub Date : 2021-09-20 , DOI: 10.1016/j.idairyj.2021.105208
Marika Bielecka 1 , Grażyna Cichosz 1 , Hanna Czeczot 2
Affiliation  

Milk proteins and the products of their hydrolysis are characterised by high levels of biological activity. The health-promoting potential of bovine milk proteins, peptides and amino acids can be attributed to their antioxidant, anti-inflammatory and immunostimulatory properties. Milk proteins, peptides and enzymes play a role in the maintenance of prooxidant/antioxidant homeostasis in the human body by scavenging free radicals, chelating metals and activating antioxidant enzymes. Lactoperoxidase, lysozyme, immunoglobulins, lactoferrin and some milk-derived peptides have antimicrobial properties. Lactoferrin exerts anti-inflammatory and immunostimulatory effects by increasing the synthesis of IgA and IgG antibodies and stimulating the production of T and B cells. The anticarcinogenic potential of bovine lactoferrin has been observed in highly metastatic breast cancer, prostate cancer, osteosarcoma, lung cancer and the gastric adenocarcinoma cell line. Milk proteins and peptides deliver health benefits by increasing the immune system's ability to identify and eliminate cancer cells.



中文翻译:

牛乳蛋白及其水解物的抗氧化、抗菌和抗癌活性——综述

牛奶蛋白质及其水解产物的特点是具有高水平的生物活性。牛乳蛋白质、肽和氨基酸的促进健康潜力可归因于它们的抗氧化、抗炎和免疫刺激特性。牛奶蛋白质、肽和酶通过清除自由基、螯合金属和激活抗氧化酶,在维持人体内促氧化/抗氧化稳态中发挥作用。乳过氧化物酶、溶菌酶、免疫球蛋白、乳铁蛋白和一些乳源肽具有抗菌特性。乳铁蛋白通过增加 IgA 和 IgG 抗体的合成以及刺激 T 和 B 细胞的产生来发挥抗炎和免疫刺激作用。在高转移性乳腺癌、前列腺癌、骨肉瘤、肺癌和胃腺癌细胞系中已经观察到牛乳铁蛋白的抗癌潜力。牛奶蛋白质和肽通过提高免疫系统识别和消除癌细胞的能力来提供健康益处。

更新日期:2021-09-20
down
wechat
bug