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Evaluation of Residual Monomers Eluted from Pediatric Dental Restorative Materials
BioMed Research International ( IF 3.246 ) Pub Date : 2021-09-18 , DOI: 10.1155/2021/6316171
Tugba Bezgin 1 , Ceren Cimen 1 , Nurhan Ozalp 1
Affiliation  

Unreacted monomers eluted from resin-based restorative materials have been considered a reason of local and systemic adverse reactions. This study was designed to determine the effect of finishing and polishing procedures on the elution of Bis-GMA, TEGDMA, UDMA, and HEMA monomers from compomer and bulk-fill composite resins. Bulk-fill composite (3M ESPE GmbH, Seefeld, Germany) and compomer (Dentsply DeTrey GmbH, Konstanz, Germany) specimens with diameters were prepared. The specimens were randomly divided into two groups, and finishing-polishing procedures were applied only to the experimental groups. Release of residual monomers was analyzed by using High-Performance Liquid Chromatography (HPLC) after 24, 48, and 72 hours. Repeated measures ANOVA and Tukey post hoc tests were used for comparisons. Finishing and polishing procedures had a significant effect on reducing the quantity of UDMA release in the Filtek™ Bulk Fill composite and Bis-GMA, HEMA, and TEGDMA in the Dyract XP compomer (). The restorative materials investigated here are not chemically stable after polymerization, and concentrations of eluted monomers may reach critical toxicity levels even after one restoration placement. Finishing and polishing procedures are mandatory to reduce residual monomers.

中文翻译:

评估从儿童牙科修复材料中洗脱的残留单体

从树脂基修复材料中洗脱的未反应单体被认为是局部和全身不良反应的原因。本研究旨在确定整理和抛光程序对 Bis-GMA、TEGDMA、UDMA 和 HEMA 单体从复合体和散装复合树脂中洗脱的影响。散装复合材料 (3M ESPE GmbH, Seefeld, Germany) 和复合材料 (Dentsply DeTrey GmbH, Konstanz, Germany) 样品直径已准备好。将试样随机分成两组,仅对实验组进行精抛光处理。在 24、48 和 72 小时后,通过使用高效液相色谱 (HPLC) 分析残留单体的释放。重复测量方差分析和 Tukey 事后检验用于比较。精加工和抛光程序对减少 Filtek™ Bulk Fill 复合材料中的 UDMA 释放量以及 Dyract XP 复合材料中的 Bis-GMA、HEMA 和 TEGDMA 释放量有显着影响()。此处研究的修复材料在聚合后化学性质不稳定,即使在放置一次修复体后,洗脱单体的浓度也可能达到临界毒性水平。精加工和抛光程序是强制性的,以减少残留单体。
更新日期:2021-09-20
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