Omphaloceles occur in about 1 in 5000 births and are the second most common congenital abdominal wall defects.1 Repair remains a surgeon’s preference with early closure only attempted for small-to-medium omphaloceles, while delayed closure is used for giant omphaloceles.2–4 In recent years, novel techniques that aim at reducing the disproportion between the abdominal cavity and the volume of the extra-abdominal viscera have been described to manage giant omphaloceles.4–17 Although less commonly associated with genetic abnormalities, giant omphaloceles are associated with adverse neurodevelopmental outcome at 2 years.18 In addition to gestational age, birth weight, associated malformation, resuscitation and hypoxia, other factors including prolonged stay in the neonatal intensive care unit (NICU), time on ventilation, infections, and delayed establishment of enteral nutrition are likely contributory factors.19 This is a case study of two infants with giant omphaloceles treated in our institution with a novel neoprene binder preoperatively. The binder allows for gradual reduction of the viscera below the level of the skin followed by early fascia closure. Families were contacted for a follow-up survey about parental experience and satisfaction in March–July 2020. A summary of the demographic and outcomes is reported in table 1. View this table: Table 1 Summary of patient’s demographic and outcomes Both infants had giant omphaloceles2 3 larger than 5 cm with most of the liver and bowel in the sac. Neither had other major abnormalities nor genetic disorders. After delivery, infants were wrapped in a plastic bag to protect the omphalocele sac and were transferred to NICU for initial care. Infants did not require sedation or intubation, and enteral feeds were started on day 1 of life, with 5 and 11 days, respectively, of concomitant parenteral nutrition until full enteral feeds were established. Immediately postnatally, the intact sac was cleaned and dressed with Restore silver dressing …

中文翻译：

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使用氯丁橡胶绑带减少巨大的脐膨出，然后延迟闭合

和延迟建立肠内营养可能是促成因素。 19 这是一个案例研究，涉及我们机构术前使用新型氯丁橡胶粘合剂治疗的两名患有巨大脐膨出的婴儿。粘合剂允许内脏逐渐减少到皮肤水平以下，然后早期筋膜闭合。在 2020 年 3 月至 7 月期间，我们联系了家庭进行关于父母体验和满意度的后续调查。表 1 中报告了人口统计和结果的摘要。查看此表：表 1 患者的人口统计和结果摘要两个婴儿都有巨大的脐膨出2 3 大于 5 厘米，大部分肝脏和肠在囊中。既没有其他主要异常，也没有遗传疾病。交货后，婴儿被包裹在塑料袋中以保护脐膨出囊，并被转移到 NICU 进行初步护理。婴儿不需要镇静或插管，从出生后第 1 天开始肠内喂养，分别伴随肠外营养 5 天和 11 天，直至建立完全肠内喂养。产后立即清洁完整的囊并用 Restore 银敷料包扎……