The Coronavirus disease (COVID-19) has spread over the world, resulting in more than 225 million patients, and 4.7 million deaths in September 2021. It also caused panic and terror, halted numerous activities, and resulted in the world economy deteriorates. It altered human behavior and compelled people to alter their lifestyles to avoid infection. Air conditioning systems are one of the most important sectors that must be considered because of the pandemic SARS-CoV-2 all over the world. Air is used as a heat transfer medium in heating, ventilation, and air conditioning (HVAC) systems. The air contains a variety of pollutants, viruses, and bacteria, all of which have an impact on and destroy human life. Significantly in summer, people spend more time in air conditioners which results in lower levels of vitamin D and melatonin which may affect the functioning of their immune system and are susceptible to receiving SARS-CoV-2 from other individuals. As an important component of air conditioning and ventilation systems, the air filter plays a significant role. As a result, researchers must work harder to improve its design to prevent the ultra-small particles loaded with COVID-19. This paper contributes to the design of existing HVAC systems in terms of their suitability and impact on the spread of the hybrid SARS-CoV-2 epidemic, as well as efforts to obtain a highly efficient air filter to remove super-sized particles for protection against epidemic infection. In addition, important guideline recommendations have been extracted to limit the spread of the SARS-CoV-2 throughout the world and to get the highest quality indoor air in air-conditioned places.

冠状病毒病 (COVID-19) 已在全球蔓延，导致 2021 年 9 月超过 2.25 亿患者和 470 万人死亡。它还引起了恐慌和恐惧，停止了许多活动，并导致世界经济恶化。它改变了人类行为并迫使人们改变生活方式以避免感染。由于全球流行的 SARS-CoV-2，空调系统是必须考虑的最重要的部门之一。空气在供暖、通风和空调 (HVAC) 系统中用作传热介质。空气中含有多种污染物、病毒和细菌，它们都对人类生活产生影响和破坏。夏天明显，人们花更多时间在空调中，导致维生素 D 和褪黑激素水平降低，这可能会影响他们的免疫系统功能，并且容易从其他人那里感染 SARS-CoV-2。作为空调和通风系统的重要组成部分，空气过滤器起着举足轻重的作用。因此，研究人员必须更加努力地改进其设计，以防止携带 COVID-19 的超小颗粒。本文有助于现有 HVAC 系统的设计，包括其适用性和对混合 SARS-CoV-2 流行病传播的影响，以及努力获得高效空气过滤器以去除超大颗粒以防止流行性感染。此外，