Many diseases are closely related to abnormal concentrations of ascorbic acid (AA), dopamine (DA), and uric acid (UA). Therefore, the detection of these small molecules is significant for monitoring life metabolism and healthy states. Electrochemical detection has been widely used to detect small molecules due to its good selectivity, high sensitivity, and good economics. Fabrication and application are two sides of the coin, and we cannot give up one for the other. Graphene (GN) is a very suitable material for electrochemical sensing due to its excellent catalytic performance and large specific surface area. It possesses many excellent properties but cannot hold itself alone due to its nanoscale thickness. Herein, we have fabricated three-dimensional (3D) GN nanosheets (GNSs) on flexible carbon cloth (CC) by thermal chemical vapor deposition (CVD). The GNSs/CC can successfully detect AA, DA, and UA simultaneously. We find that these GNSs/CC sensors show good performance with 7 h CVD modification. The linear ranges of AA, DA, and UA are 0.02–0.1, 0.0005–0.02, and 0.0005–0.02 mM, respectively. The detection sensitivity rates of AA, DA, and UA are 5,470, 60,500, and 64,000 μA mM⁻¹ cm⁻², respectively. Our GNSs/CC flexible sensors can be successfully applied in the human serum for UA detection. The result matches with commercial sensors very well.

许多疾病与抗坏血酸（AA）、多巴胺（DA）和尿酸（UA）浓度异常密切相关。因此，检测这些小分子对于监测生命代谢和健康状态具有重要意义。电化学检测因其良好的选择性、高灵敏度和良好的经济性而被广泛应用于小分子的检测。制造和应用是硬币的两个面，我们不能为了另一个而放弃一个。石墨烯（GN）由于其优异的催化性能和大的比表面积，是一种非常适合电化学传感的材料。它具有许多优异的性能，但由于其纳米级的厚度而无法单独保持。在这里，我们通过热化学气相沉积（CVD）在柔性碳布（CC）上制造了三维（3D）GN纳米片（GNS）。GNS/CC 可以成功同时检测 AA、DA 和 UA。我们发现这些 GNSs/CC 传感器经过 7 小时 CVD 修饰后表现出良好的性能。AA、DA 和 UA 的线性范围分别为 0.02–0.1、0.0005–0.02 和 0.0005–0.02 mM。AA、DA和UA的检测灵敏度分别为5,470、60,500和64,000 μA mM ^-1 cm ^-2。我们的 GNSs/CC 柔性传感器可以成功应用于人血清中的 UA 检测。结果与商业传感器非常匹配。