Mounting evidence supports a mechanistic association between irritable bowel syndrome (IBS) symptoms and mast cell hyperactivity. Yet, association between IBS and mast cell disorders (MCDs) has not been studied. We examined this association using two large databases and verified with manual chart review.

中文翻译：

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肠易激综合征与原发性和特发性肥大细胞疾病密切相关

越来越多的证据支持肠易激综合征 (IBS) 症状与肥大细胞过度活跃之间的机制关联。然而，尚未研究 IBS 与肥大细胞疾病 (MCD) 之间的关联。我们使用两个大型数据库检查了这种关联，并通过手动图表审查进行了验证。