This communication reports a novel synthesis route for the preparation of monofunctionalized β-cyclodextrin in a single stage. The approach involves only the in-situ protection of secondary hydroxyl groups as an excellent alternative to the classical procedure involving a series of five steps of protection and deprotection of hydroxyl groups (both primary and secondary ones) belonging to β-cyclodextrin.

中文翻译：

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使用铜复合夹层保护策略选择性甲基化 β-环糊精的简单合成路线

该通讯报道了一种单阶段制备单官能化β-环糊精的新合成路线。该方法仅涉及仲羟基的原位保护，作为经典方法的极好替代方案，该方法涉及一系列五个步骤，包括对属于β-环糊精的羟基（伯羟基和仲羟基）进行保护和脱保护。