Breast cancer (BC) is the most commonly diagnosed cancer among women worldwide and the most common cause of cancer-related death. To date, it is still a challenge to estimate the magnitude of the clinical impact of physical activity (PA) on those parameters producing significative changes in future BC risk and disease progression. However, studies conducted in recent years highlight the role of PA not only as a protective factor for the development of ER+ breast cancer but, more generally, as a useful tool in the management of BC treatment as an adjuvant to traditional therapies. In this review, we focused our attention on data obtained from human studies analyzing, at each level of disease prevention (i.e., primary, secondary, tertiary and quaternary), the positive impact of PA/exercise in ER+ BC, a subtype representing approximately 70% of all BC diagnoses. Moreover, given the importance of estrogen receptors and body composition (i.e., adipose tissue) in this subtype of BC, an overview of their role will also be made throughout this review.

中文翻译：

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绝经后女性雌激素受体阳性乳腺癌：身体成分和体育锻炼的作用

乳腺癌 (BC) 是全世界女性中最常被诊断出的癌症，也是癌症相关死亡的最常见原因。迄今为止，估计身体活动 ( PA ) 对那些在未来 BC 风险和疾病进展中产生显着变化的参数的临床影响程度仍然是一个挑战。然而，近年来进行的研究强调了PA不仅作为 ER+ 乳腺癌发展的保护因素的作用，而且更普遍地作为传统疗法的辅助治疗 BC 治疗的有用工具。在这篇综述中，我们将注意力集中在从人类研究中获得的数据上，这些研究分析了在疾病预防的各个层面（即一级、二级、三级和四级），PA / ER+ BC 中的运动，该亚型约占所有 BC 诊断的 70%。此外，鉴于雌激素受体和身体成分（即脂肪组织）在这种 BC 亚型中的重要性，本综述还将对其作用进行概述。